Mega Cancer Study Shatters Vegan Myth

A massive new cancer study is puncturing the “vegan equals healthier” talking point with an unsettling twist: vegans showed a higher colorectal cancer risk than meat-eaters.

Story Snapshot

  • Researchers analyzed data from more than 1.8 million people across the US, UK, India, and Taiwan over an average 16-year follow-up.
  • Vegetarians showed lower risks for five cancers, but the vegan subgroup showed a higher colorectal cancer risk compared with meat-eaters.
  • The study is observational, meaning it can spot associations but cannot prove diet caused the outcomes.
  • Experts pointed to possible nutrient shortfalls—especially low calcium intake—as a plausible factor worth investigating.

What the Largest-Ever Dataset Found—and Why It Surprised People

Oxford Population Health’s Cancer Epidemiology Unit reported results from what it described as the largest study to examine non-meat diets and cancer outcomes, tracking 17 cancer types across multiple long-running cohorts. The headline finding cut against a popular cultural assumption: while vegetarian patterns were linked with lower risks for several cancers, the vegan subgroup showed a higher risk of colorectal cancer than meat-eaters. Researchers stressed the finding does not establish cause-and-effect.

That nuance matters because the dataset spans decades and draws from populations that often have healthier baselines than the general public. Several cohorts included people who already ate relatively low amounts of processed meat, which can narrow differences between groups. The study’s global reach adds strength, but it also means diet patterns and food availability varied widely by country and era, complicating simple “diet label” conclusions.

Vegetarian Benefits Showed Up—But Not Everywhere

The same analysis found vegetarian diets were associated with lower risk for five cancers, including breast, prostate, kidney, pancreatic cancer, and multiple myeloma. That aligns with a long-standing body of research suggesting plant-forward eating can improve health markers when it emphasizes whole foods. The new wrinkle is that the expected colorectal advantage for strict non-meat diets did not clearly materialize in the vegan subgroup—raising questions about which nutrients, not slogans, drive risk.

Researchers and external commentators emphasized that “vegan” and “vegetarian” are not magic words; they describe exclusions, not guaranteed nutritional adequacy. A diet can be meat-free and still be low in critical micronutrients or high in heavily processed foods. The study’s authors and outside experts urged follow-up work because the vegan sample was much smaller than the overall pool, which can make subgroup results more sensitive to quirks in the data.

Why Calcium and Fortification Became the Center of the Discussion

One leading explanation raised by researchers was low calcium intake among vegans, a concern tied to reduced consumption of dairy and other common calcium sources. Prior research has reported protective associations between higher calcium intake and lower colorectal cancer risk, which makes calcium a plausible pathway to investigate. The study also raised the reality that modern vegan diets may differ from older versions because fortified foods and supplements are more common today.

That point is important for readers trying to apply the findings in real life: much of the diet data reflects earlier eras, before today’s explosion in fortified plant milks and engineered meat substitutes. Experts cautioned that older cohorts may not represent a 2026 vegan shopping cart. In other words, the study is a significant warning flag—not a final verdict—about colorectal risk in vegan populations, particularly when nutrition planning is sloppy.

What This Means for Families Trying to Eat Healthy Without Ideology

For everyday Americans, the practical takeaway is less political than the culture war around food often makes it: focus on nutrient sufficiency and minimize ultra-processed junk, regardless of whether a menu includes animal products. The research also reinforces a consistent theme across cancer prevention guidance—processed meat is not a health food, and “more plants” can be beneficial when it increases fiber, fruits, and vegetables while keeping essential nutrients covered.

Limited details are available in public reporting about how specific vegan food choices (whole-food plant-based versus highly processed alternatives) differed within the cohort data, and the authors emphasized the need for updated research that reflects current diets. Until then, the study offers a caution to anyone treating dietary identity as a substitute for careful nutrition: broad labels can hide real deficiencies, and those deficiencies may matter for colorectal cancer risk.

Sources:

A new study suggests vegans have a higher risk of colorectal cancer — but meat-eaters aren’t in the clear

Largest study of vegetarian diets and cancer shows lower risk of five cancers

Study shows vegetarian diets have reduced risk of medium-frequency cancers

Expert reaction to study looking at vegetarian and other diets and incidences of different cancers

New poll: Almost half of US adults unaware of connection between processed meat

Largest study of vegetarian diets and cancer shows lower risk of five cancers